College Football Odds, Picks, Predictions For Week 1, 2022

 

College football is king in the sports world over Labor Day weekend, and the Week 1 schedule does not disappoint in 2022. The headliner is No. 2 Ohio State vs. No. 5 Notre Dame on Saturday evening. But there are plenty of other matchups to look forward to such as No. 3 Georgia vs. No. 11 Oregon, No. 7 Utah vs. Florida and No. 19 Arkansas vs. No. 23 Cincinnati.

The latest Week 1 college football odds from Caesars Sportsbook list the Buckeyes as 17.5-point favorites over the Fighting Irish. The Bulldogs are -17, the Utes are -3 and the Razorbacks are -6. Whether you're looking to lay down a bet on one of those Week 1 college football spreads or any others over the course of the long weekend, there's a lot to consider. Before locking in any Week 1 college football picks, be sure to see the latest college football predictions from SportsLine's advanced computer model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,600 for $100 players on its top-rated college football picks against the spread. It enters Week 1 of the 2022 college football season on a 45-32 run on all top-rated college football spread and money-line picks that dates back to 2021. Anyone who has followed it has seen huge returns.

Now, it has turned its attention to the latest Week 1 college football odds from Caesars and locked in picks for every FBS matchup. Head here to see every pick.

Top college football predictions for Week 1

One of the college picks the model is high on in Week 1: Florida (+3) covers at home against No. 7 Utah at 7 p.M. ET on Saturday. The Gators are led by an outstanding quarterback in Anthony Richardson, who is a high-level NFL prospect. First-year head coach Billy Napier brought in several key pieces from his Louisiana offense, and he is going to have a strong offensive line.

The Gators also have an excellent rushing attack, giving them the pieces to be effective right away against Utah. There is going to be a large crowd on hand for a night game at The Swamp, making life difficult for the visiting Utes in a cross-country travel spot. SportsLine's model expects Richardson to record more than 320 total yards, which is one reason why the Gators are covering the spread almost 60% of the time. 

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